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To: Cc: Dr. George Church[ From: Joseph Thakuria Sent Thur 8(1/201312:03:44 PM Subject Re: Jeffrey Epstein Hi M, Jeffrey's skin biopsy resulted in several successful, viable fibroblast cultures. Those cell lines are now stored in liquid nitrogen and slated for iPS cell line ("adult stem cells") creation. Essentially, this process requires several culture passages, and reiteration of picking out the right colony for further passages. Success rate of generating iPS cells is relatively high now but the process still takes several months. On the DNA side of things, I'm working on getting Jeffrey's sample into the current queue. If it makes it, we're probably looking at about 2 months turnaround time until whole genome data. Let me know if I can help with other questions. Best, Joe Joseph V. Thakuria, MD, MMSc Medical Genetics and Metabolism Attending Physician Director, MGH Stickler Syndrome Program Medical Director, Personal Genome Project Harvard Catalyst CRC Protocol Review Committee MGH Center for Human Genetics Research Massachusetts General Hospital 185 Cambridge St., Rm. 2222 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. On Thu, Aug 1, 2013 at 7:43 AM, rote: Good morning George and Joe. Jeffrey requested I check in and see how things arc progressing with his genome. Could you please advise? Thank ou, EFTA_R1_00779457 EFTA02133204 Assistant to Jaffe Epstein Sent from my iPhone EFTA_R1_00779458 EFTA02133205