From: Boris Nikolic

From: Boris Nikolic To: "Jeffrey Epstein I III ) " Subject: FW: Materials at request of David Rubenstein Date: Fri, 11 Mar 2011 03:17:41 +0000 Attachments: NaviMed_Global Health Partners FINAL_1-7-11.pptx; Project_River_- Short Overvievaoc _ _ From: Ryan Schwarz [mallto Sent: Wednesday, Mardi 09, 2011 11:28 AM To: Boris Nikolic Subject: Materials at request of David Rubenstein Boris, David asked me to send you the two attached documents before our meeting tomorrow. One is a high-level concept piece on the global healthcare venture fund idea that we prepared to help David introduce the concept to folks around Carlyle. It provides an overview of the market opportunity as we see it, though of course with much less detail around investment strategy and emphases than will be included in the eventual fund placement memo and presentation. The other is a confidential summary of an investment opportunity that we are pursuing involving Xigris, the sole approved, on-market drug for severe sepsis. I look forward to seeing you in the morning. Ryan Ryan M. Schwarz Managing Director THE CARLYLE GROUP 1001 Pennsylvania Ave. =. Washington, DC 20004 202-347-2626 202-347-1818 fax 202-729-5334 direct 202-285-3167 mobile < CONFIDENTIALITY NOTICE > The information contained in this transmission is intended only for the person or entity to which it is addressed and may contain confidential, trade secret and/or privileged material. If you are not the intended recipient of this information, do not review, retransmit, disclose, disseminate, use, or take any action in reliance upon, this information. If you received this transmission in error, please contact the sender and destroy all printed copies and delete the material from all computers. EFTA00682418