Harvesting Nature's Intelligence

Harvesting Nature's Intelligence PROT0 Developing forces in the ecosystem Consumers want food products to be a trusted source of health Plants are a vast and still untapped source of natural solutions Brightseed discovers compelling natural solutions with unprecedented speed • brightseed 2 PROT1 Nature has always held the solution Universe of plant compounds More than 99.9% of plant compounds have yet to be discovered I or • s 'Ibi ' \ 5 to - - "1 '4 4;; 0 . .:-Al* •, I's v i 10 000' '' w - rN4A,_ .,...0.1•1 V , 1.. Known plant compound's --,...-1.-_: ,,•e:'-",'4 , '!'-:;if''..-- .14 3 brightseed PROT2 Brightseed unleashes nature's intelligence in food brightseed Brightseed's discoveries transform today's food CPG products into a scientifically proven source of health By restoring the central role of plants and their healthful compounds in nutrition, we can reconnect every person to the goodness in,the foods they eat 4 PROT3 brightseed Brightseed built ForagerTM, nature's discovery engine ▪ Brightseed created Forager, a computational intelligence that understands nature more profoundly than human intelligence • Forager is fueled by Brightseed's growing proprietary data on the world's plants and deep knowledge of human biology • Forager interrogates and learns natural phenomena with unprecedented speed and scale, discovering natural compounds that solve unmet human problems 5 PROT4 We find authentic sources of health compounds, faster Plant compound space •• 4. 1 • s % • 6 0 0 0 r. t •,, c Alt._ % • C 8 s ,0". 1 • ,q, SV S • s f..• • JD • a b . l " .le ,I. - b- k u. • 8 % . •il• . • lb • •t• 0 . • 0 A. 1 a a% 0. ef. al. 3 e. ' I) - a • amino acid carbohydrate cofactor fatty acid hot mone lipid nucleotide secondary metabolite vitamin Human metabolism 6L... -mamma- *6; ••4 '73.7.7r.'"- - -jr If; T 4444. 6 s: brightseed PROT5 Magellan, our first discovery, boosts metabolism -.3t - 1--.Vw; .' '-, t. ),%ti:-.:,%•;1" ce-.,n a 4, 4- i ..., •• 4 4 \/:,1.41, ,' , i... A "ti. 1, •-e• • • v 4 \ V, i 1, I.: , : * 7 - A I. 4 ti 0 ' '..t.'-,.-c-"SO4 t i ' it, y. ' 7 g k A i z''. * ii ",_ k ilt( •(.., 4 6 ' 1., `.:l' - ct 4 k.'i:;- /i : - J 0 , i It Ij c • - firP*0' r - $ .' 1 5 'ir r..Tio ir ".., 4p,- • - lit t'i ' .5 , 4c. . .i ,. • :.; -4 .-J o. i. - 1 ,7A ., 7--•rpo 1P,rili • s... , • .., 40 • Today's diet impairs our normal metabolic regulation, '-'..: exposing us to the dangers of chronic illness such as :,,inI., , o• ..ir - , • ii .,, • I - p•P' "--,;;;-*, -41-iir.:*. 1 11, . ...., C4 .. *.t cardiovascular disease, diabetes, and liver disease ',L -'..-, k ''.1. ...b • Itr.; r. a •:2.14.b ,t. Ira, 1 l ' 4 V V r •L• ...1 . ( ; ,a73D, 4: i. i ., i r , ', p op ,i, ..; • Magellan is a natural plant compound that boosts . \ V . 4*...44: - _dr ., .. - -, . - 71,-?4 A the body's natural ability to regulate its metabolism - • l',..,c 'It -. - -. ... I• PA .',,..* e'..e, 4 - 4, : `'2, 14-- `, ' • Magellan works through a clinically proven 4. V ...! ',I. ' et-'. - I:.414 I. \ "i,, 1 :t ,e'l % I 41,. ....t t,i..? 4 1 k. .... 7 t A cki mechanism of action, allowing the body to counter ;,: ,' •544r7r,-, ', .'_,:it•!.oria :tjj *-;), , I. s -, .." pp.:7 1 1.=.* 4-- #• * t ''' '' .t4a % /C Fr i . - the adverse effects of modern food .v, 4.,..) a. - _i r -, r.- t • e .. ..,-- ., ills I.' _ ,, I tt..•• lA , %ft - s ' . a, 6. '3- . •i. fs' ! tt ,, ,, , - • 4 - ' *47 . 51.1. • Patents are pending on composition, methods, and ,., 4,,-e • :-tip ,.. .14-4 g ? 71 , '''')., 41- ,"in - .--r ,,..-.• et, , . • y, 0 - -; • A process -, .04 v,,, ,, 4 7* 1 ..t e ' ill' : 1'. 41 A . .0 ' &A' it. 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YPPL'Nv:-. ,, 11,1 ,z-jb:... *a .,.,14 .• 7 brightseed PROT6 Magellan benefits reconnect consumers with brands "Naturally clears harmful fats" "Plant-powered body regulator" "Awaken your body's natural restorative powers" 8 % brightseed PROT7 Why partner with Brightseed Offer proven health benefits Magellan - Embed Magellan as a plant bioactive in food, beverage or supplements with category exclusivity - Provide consumers with purpose driven consumption, authentically Rapidly transform strategy to product Forager - Deliver plant-based solutions for strategically relevant health benefits in your product portfolio - Unlock the intrinsic health benefits of your existing supply chain brightseed 9 PROT8 Accomplished management team 10 Jim Flatt, PhD Co-founder and CEO Biosciences leader with track record of translating breakthrough discoveries and leading-edge technology into commercially successful products, including nutritional lipids at Martek Biosciences, renewable products at Synthetic Genomics, renewable biofuels at Mascoma and food technology at Hampton Creek. MIT Chemical Engineer, University of Wisconsin PhD. Lee Chae, PhD Co-founder and CTO Computational and molecular biologist leader with a track record of designing cutting-edge discovery methodologies for biomedicine, synthetic biology, agricultural biotech and food technology. Principal scientist in discoveries, including machine-learning driven identification of functional food proteins and computationally driven screens for novel metabolic genes and nutritional plant bioactives. UC Berkeley PhD, Stanford Carnegie Institute of Plant Biology. www.brightseedbio.com Sofia Elizondo, MBA Co-founder and COO Business leader with a track record of business model innovation working with consumer goods, pharmaceutical and technology companies. Former researcher at the BCG Henderson Institute and advisor to the United Nations. Launched, grew and managed multi-million dollar business lines in online and food technology venture-backed startups in Silicon Valley. Stanford Graduate School of Business MBA. Carol Lynn Berseth, MD SVP Medical and Scientific Affairs Executive leader bridging technical and commercial teams for novel health product launches. Former Medical Director in Global Clinical Innovation at Mead Johnson. 15+ years clinical experience and academic research leadership at Mayo Clinic and Texas Children's Hospital. Drove portfolio of over 60 global clinical trials supporting over 200 global product launches. brightseed PROT9 Top-tier advisory team Bernhard van Lengerich, PhD Former Chief Science Officer of General Mills General Mills Peter Domaille, PhD Widely published researcher in analytical quantitation and structure elucidation SYNTHETIC GENOMICS 0 MERCK 11 tJPON) SBP Fred Levine, MD, PhD Biochemical genetics and inherited metabolic diseases specialist. Director of Sanford Health Research Center Sanford Burnham Prebys MEDICAL DISCOVERY INSTITUTE Jed Fahey, ScD Nutritional biochemist and expert in plant physiology, human nutrition and biochemistry, Director of the Chemoprotection Center at Hopkins University JOHNS HOPKINS SCHOOL of MEDICINE Valerio Nannini, MBA Former SVP Head of Strategies and Performance of Nestle, former head of Nestle Singapore 15 7 Expert in process and product development in industrial biotech and food tech. Advisory positions at Bolt Threads, Amyris, Miraculex AMYRIS. Jason Ryder, PhD n Bolt V Threads John SanGiovanni, PhD Chief of Unit on Genetics in Nutritional Neuroscience, National Institutes of Health, Professor Georgetown School of Medicine Trent Northen, PhD Director of High-Throughput Biochemistry at the DOE Joint Bioenergy Institute and metabolomics leader at the DOE's Joint Genome Institute L, La e Lawrencee National Laboratory brightseed PROT10 Supported by world-class investors CGC Horizons entures fit ;*#',11:1 12 Y 50 GERMIN8 AWUNDER •: brightseed PROT11