EFTA Document EFTA02086352

To: Joe Thakuria Fran: Lesley Groff Sent Fri 1/9/2015 1:31:20 PM Subject Re: Any Update for Jeffrey Epstein Hi Joe...any update? :) Lesley On Dec 9, 2014, at 6:17 PM, Joseph Thakuria wrote: OK, we'll do a deep dive on those gene associations for his data. On Tue, Dec 9, 2014 at 6:00 PM, Lesley Groff-: wrote: Jeffrey replied back! He says: diabetes and kidney issues! Thanks so much! On Dec 9, 2014, at 5:06 PM, Joseph Thakuria wrote: Please stress that providing the info is completely voluntary. Theoretically it should make for a more personalized analysis and it gives him the opportunity to let me know if there is any medical condition he specifically wants me to do a deep dive with his data on. (The general screen for medically serious mutations will happen of course even without any additional info from him.) Joe On Tuc, Dec 9, 2014 at 4:54 PM, Lesley Groff wrote: Hi Joe! thank you so very much for the update...I am not sure if Jeffrey would like to provide any family medical history but will ask and get back to you...great to know things are moving along!! On Dec 9, 2014, at 4:28 PM, Joseph Thakuria wrote: Hi Lesley, sorry for not replying earlier. I'm analyzing data now on the exomes we've sequenced. Jeffrey's raw data should be available soon 2-3 weeks and I expect everything to be wrapped up the end of this month. Do you know if Jeffrey wants to voluntarily provide any personal medical or family medical history? We can EFTA_R1_00675214 EFTA02086352 personalize the analysis based on this info. For example, for people with a strong family history of breast cancer, I can make sure we do a thorough look at breast cancer associated genes in addition to the basic analysis for these individuals. Specifically, family medical history on sibs, parents, and grandparents can be useful - as well as any history of inherited disorders - especially if it is rare and early onset in life. Thanks in advance for passing on this info. Best, Joe On Dec 8, 2014 12:46 PM, "Lesley Groff" wrote: Hello Joe! Checking in...anything to report to Jeffrey? Please let me know where you are with this project... thanks! Lesley Assistant to Jeffrey Epstein EFTA_R1_00876215 EFTA02086353