EFTA Document EFTA02127509

To: Joseph Thakurirl Cc: George Church From: Lesley Groff Sent Thur 9/19/2013 4:35:00 PM Subject Re: Jeffrey Epstein Hello Joe! Hope you are doing well! Jeffrey is 'checking in'...might you have any new news regarding his genome? (Were you able to get Jeffrey's DNA in the queue?!) Any update would be tremendous. Thanks, Lesley On Aug 1, 2013, at 9:50 AM, Joseph Thakuria wrote: My pleasure, Lesley. Give him my regards. Joe On Thu, Aug 1, 2013 at 9:43 AM, Lesley Groff ‹ > wrote: Terrific! I will pass this along to Jeffrey...if he has any questions we will let you know! Thanks and have a great day. Lesley On Aug I, 2013, at 8:03 AM, Joseph Thakuria wrote: Hi Lesley, Jeffrey's skin biopsy resulted in several successful, viable fibroblast cultures. Those cell lines are now stored in liquid nitrogen and slated for iPS cell line ("adult stem cells") creation. Essentially, this process requires several culture passages, and reiteration of picking out the right colony for further passages. Success rate of generating iPS cells is relatively high now but the process still takes several months. On the DNA side of things, I'm working on getting Jeffrey's sample into the current queue. If it makes it, we're probably looking at about 2 months turnaround time until whole genome data. Let me know if I can help with other questions. Best, Joe EFTA_R1_00767298 EFTA02127509 Joseph V. Thakuria, MD, MMSc Medical Genetics and Metabolism Attending Physician Director, MGH Stickler Syndrome Program Medical Director, Personal Genome Project Harvard Catalyst CRC Protocol Review Committee MGH Center for Human Genetics Research Massachusetts General Hospital 185 Cambridge St., Rm. 2222 Boston, MA 02114 Office: Fax: email: The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. On Thu, Aug I, 2013 at 7:43 AM, Lesley Groff O> wrote: Good morning George and Joe. Jeffrey requested I check in and see how things are progressing with his genome. Could you please advise? Thank you, Lesley Assistant to Jeffrey Epstein Sent from my iPhone EFTA_R1_00767299 EFTA02127510